New RSV Antibodies
Specific for RSV Fusion Protein
RSV is considered the most important respiratory pathogen in childhood and can be fatal for infants less than 6 months old. There are two main types of RSV (A and B) and many subtypes (strains) although the most prevalent and virulent is subtype A. The virus has two major surface glycoproteins (G & F) that play important roles in the initial stages of the infectious cycle. Specifically the F (fusion) protein mediates entry of the virus into the cell cytoplasm and also allows the formation of syncytia. The Fusion protein is homologous in both types of RSV.
Various diagnostic tests are available for RSV diagnosis, however most laboratories rely on antigen detection tests (specifically direct immunofluorescence) and supplement with cell culture. The recent availability of excellent monoclonal antibodies has increased the sensitivity of rapid assays to between 80% and 97%. Meridian Life Science just released 9 new monoclonal antibodies to RSV fusion protein. These antibodies were made using native RSV antigen (Long strain) and are specific to RSV types A and B and do not cross-react with Influenza A virus, Influenza B virus or Adenovirus.
NEW RSV MONOCLONAL ANTIBODIES
Specific for RSV Fusion Protein of both A and B RSV strains.
No cross reaction with Influenza A virus, Influenza B virus or Adenovirus.
|C01770M (IgG1a)||C01773M (IgG1) Detection|
|C01771M (IgG2a)||C01775M (IgG2a) Capture|
OTHER POPULAR RSV PRODUCTS
|C65063M||MAb to RSV Fusion Protein (PAIR – Capture)|
|C65065M||MAb to RSV Fusion Protein (PAIR – Detection)|
|B65860G||Goat anti-RSV (All Antigens to RSV-A and RSV-B)|
|C66432M||MAb to RSV Nucleoprotein|
|8175||RSV Antigen, Long Strain (partially purified)|
|R86900||RSV Antigen, Long Strain (purified)|