Molecular diagnostic tests are progressively moving towards a lyophilized format. There are several advantages for this, including room temperature shipping and storage, extended shelf-life and increased flexibility in sample volume. In order to be compatible with lyophilization however, enzyme preparations must be glycerol-free and include specialized lyophilization-excipients that preserve the mixture as it is exposed to various lyophilization conditions including freezing, temperature ramps, vacuum and dehydration. An ideal lyophilization formulation should stabilize an enzyme in a freeze-dried format and allow very fast rehydration and reactivation of the enzyme preparations, without impacting its performance post rehydration. Meridian’s range of lyophilization-ready mixes are also available as components in order to fit into your assay development.