Tropical and vector-borne diseases are among the most complex of all infectious diseases to prevent and control. Tropical diseases typically thrive in hot, humid conditions. Many of these pathogens are also vector-borne diseases, transmitted between humans by a vector which is typically a blood-sucking anthropoid (e.g. mosquitoes, ticks, fleas, lice and mites). Serological point-of-care (POC) diagnostics are the most rapid and convenient methods available for tropical and vector-borne diseases. Tests either detect antigens from the infectious agent or virus specific IgG/IgM antibodies and include formats such as solid-phase dip-sticks (ELISA), particle agglutination, and lateral flow. Ideally screening assays should have minimal cross-reactivity with other infectious diseases and have a high sensitivity, especially during the early stages of the infection.
Meridian offers a range of antibodies and antigens ideal for developing sensitive and specific assays. Download a catalog to learn more about methods that can be used to reduce cross-reactivity in flavivirus assays and improve IgM detection sensitivity.