ToRCH is an acronym for a group of infections that can cause congenital abnormalities and it has become an important part of prenatal care to recognize these infections in the first trimester of pregnancy.
For most ToRCH organisms, the initial screening test is based on the detection of antibodies (IgG and IgM) to the organism. Subsequent screening, if required, is carried out using a monoclonal antibody-based immunofluorescent assay (IFA). In most cases, IgG reactivity in the absence of IgM is indicative of a past infection, while IgM reactivity in the absence of IgG indicates a current infection.
Meridian Life Science offers a range of reagents which are suitable for multiple assay formats, including IgM and IgG antibody detection, rapid anti-IgM assays, and Immunofluorescence assays (IFA) for the ToRCH test and other Childhood diseases.