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Meridian Biologics has extensive experience in the purification of secreted and cell-associated proteins by conventional, proprietary and specialized methods for over 20 years. We can adjust to your purification procedures, adapt our procedures, or develop new procedures.

Meridian Biologics’ harvest and purification capabilities include:

• Centrifugation and Gradient centrifugationAll forms of filtration including Tangential Flow FiltrationMicrofluidization for processing of cells prior to purificationIon exchange, affinity, size exclusion, and, hydrophobic chromatographyDedicated columns sized for each client's project needsExpanded bed "attachment-based" chromatography for purification of proteins from microfluidized/unfiltered cell lysates and perfused mediaChromatography and filtration under clean room conditions
• cGMP ÄKTApilot™ and ÄKTAexplorer™ purification system with flow rates up to 800ml/min